The anti-infective guidelines of the University Hospital Leipzig (UKL), which were first published in 2014, were published in the second edition as an app at the end of 2016. The third edition followed at the end of 2018, the fourth at the end of 2020 and the completely revised and updated fifth edition at the end of 2022. The members of the UKL Anti-Infectives Commission have compiled diagnostic information and recommendations for therapy and prophylaxis with antibiotics and anti-infectives in a clear manner, supplemented by information on important hygiene standards. The scope includes adult patients, but also children and adolescents via special chapters. In addition to the use of anti-infectives, there are clear recommendations on how to proceed in patients with unclear fever as well as information on the individual drugs (use during pregnancy, dose adjustments in the event of renal insufficiency, etc.).

Prof. Dr. Christoph Lübbert, who was responsible for creating the guidelines, sees a decisive advantage over general guidelines: "We recognize exactly which problems and requirements we are confronted with in our everyday life and can react to them extremely quickly with the guidelines or our app. Within just a few months, new information is incorporated and thus made available to the colleagues working on the patient.”

Despite the precise tailoring to the needs of inpatients at the Leipzig University Hospital, use is also possible elsewhere, but should then include an adaptation to the locally prevailing pathogen and resistance situation. If applied consistently, the recommendations given can make a significant contribution to optimizing the use of antibiotics or anti-infectives, reducing consumption and thus also preventing the development of resistance and improving patient safety.

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